Principal Scientists head the research teams and use their knowledge and experience to guide the juniors and peers. Standing at the forefront in research and development programs, the Principal Scientists execute the following job description – leading in research efforts, developing better ways to execute the project, planning and scheduling project, mentoring other researchers, conducting tests and evaluating performance, conducting qualitative and quantitative research to improve existing one, providing technical guidance, and monitoring staff performance.
Principal Scientists are supposed to have an analytical mind and have a strong commitment to scientific processes, they should have sound researching methodologies, and possess math based reasoning skills. These scientists must be capable decision makers and as well have a detailed knowledge of relevant technology and understand thoroughly the functioning of test materials. Most often, employers want the Principal Scientist Resume to mention a Doctoral degree in the related scientific field.
Summary : Highly qualified Principal Scientist with experience in the industry. Enjoy creative problem solving and getting exposure on multiple projects, and the collaborative environment on which your company prides itself.
Skills : Drug product commercial aseptic operation, Process Development, Manufacturing.
Description :
Research and identify new technology for disruptive product benefits across multiple business sectors; propose resources and align with senior management strategic initiatives; link technology to key category needs within the business sectors e.g.
Led identification of new technology space providing potential for transforming products across multiple business units as part of an effort to establish the 'Transformative Platform Technology' department.
Achieved support for 'energy has driven' technology concept and obtained alignment on light-driven processes as the initial focus.
Collaborated with business units, identifying transformative benefit opportunities for light driven technology.
Established light has driven group and capability, allowing new technology development for business needs.
Conceived and developed technology, delivering against transformative benefit opportunities; leading to new technology for application in key business units.
Developed a gradient polymer elution chromatography (GPEC) method for polymer characterization on drug-eluting stents.
Experience
7-10 Years
Level
Management
Education
Philosophy
Principal Scientist III Resume
Headline : A passionate and accomplished researcher with more than 12 years of scientific research at academic institutions and 10 years of R&D experience in the Biotechnology industry. Multidisciplinary expertise with extensive knowledge and hands-on experience. Track record of R&D project initiation, design, implementation and execution. Scientific and technical leadership with strong strategic planning, analytical thinking and problem solving aptitudes.
Skills : Biotechnology Skills: Biotechnology, Medical Devices,.
Description :
Led design, development, evaluation, validation and launch of novel tissue preservation systems.
Responsible for planning, designing, implementing, executing and reporting of numerous R&D studies, including market analysis, strategic planning, product design, safety and efficacy assessment, risk management, design transfer, and process validation.
Launched systems extended shelf life of tissue grafts from 7 weeks to 12 weeks, significantly increasing product availability, reducing graft loss and expanding company portfolios.
Developed executable strategies for new product development based on the findings of market analysis, literature search, and scientific investigation.
Product development: led the R&D team through the entire life cycle of new product development, from unmet need analysis, concept generation, feasibility assessment, product design, intellectual property clearance, risk analysis, process validation to product launch.
Compiled the project plans by establishing objectives, timelines, budgets, procedures, and milestones.
Monitored the project progress to ensure the expected results are delivered on schedule.
Experience
5-7 Years
Level
Executive
Education
Doctor Of Philosophy
Principal Scientist II Resume
Headline : Motivated and productive Ph.D. scientist with over 10 years of experience in immuno-oncology, cancer immunotherapy, tumor immunology, cell immunology, cellular immunology, mucosal immunology and vaccine development.
Evaluation and development of new drug delivery technologies for the Pharmaceutical, OTC and Nutritional Supplement markets.
Design and prepare oral dosage form test prototypes for animal and human studies.
Plan and execute pK studies to investigate drug release profiles and bioavailability improvement.
Review all data and technical reports and make recommendations on next steps and follow up studies.
Evaluation and development of new formulations/concepts for injected molded capsule platform.
Application of hot-melt extrusion to capsule release profiles, including immediate release, modified release and enteric release.
Formulation development of hot-melt extrusion drug/polymer particles with increased solubility and bioavailability.
Experience
5-7 Years
Level
Executive
Education
M.S. In Chemistry
Principal Scientist I Resume
Objective : Extensive experience in formulation of suspension based products. Lead inventor of patents covering two major pharmaceutical products. Very strong knowledge of wet bead milling, colloid and surface science, materials science and physical chemistry.
Provided/supported the development of intellectual property.
Managed the successful development of two nanoparticulate formulations and associated manufacturing processes.
Demonstrated feasibility of using gamma radiation and heat for finished product sterilization.
Directed research aimed at understanding the underlying mechanisms producing particulate impurities.
Experience
2-5 Years
Level
Executive
Education
Physical Chemistry
Sr. Principal Scientist Resume
Summary : Ph.D in biochemistry, with 8 years of industry experience in age-related eye diseases and immuno-oncology fields. Expertise in neuroscience, retinal biology and cancer biology combined with the experience in the protein engineering.
Skills : Yeast two hybrid system, DNA Cloning, Adenovirus/Retrovirus.
Description :
Developed novel virus filtration membranes based on polyvinylidene fluoride and polyethersulfone.
Process optimization produced a membrane with a narrow pore size of about 20 nm and a 20 kg/m2 protein capacity at 75% flux decay.
Released PVDF membrane for marketing after completing IQ, OQ and PQ in production.
Developed new formulations for supported microfiltration membranes and scaled them up at the membrane casting machines.
Applied mixture design to optimize the formulation and finished the project 10 months earlier than planned.
Solved a production issue for an asymmetric microfiltration membrane using Six Sigma methodology.
Production efficiency increased 100% because of the process improvements implemented, resulting in $1M savings.
Controlled the extractables from hydrophilic polypropylene membranes by introducing a new UV curing system and optimizing the process.
Experience
10+ Years
Level
Senior
Education
M.Sc. In Chemistry
Asst. Principal Scientist Resume
Objective : An accomplished, innovative research scientist and a technical leader in analytical chemistry. Expert in driving development of new analytical technology utilizing state of the art instrumentations.
Design and develop QA/QC procedures and standards for new Solstice yf refrigerant products.
Assist in new distributor plant startup and implement Honeywell QA standards in distributor's analytical facilities.
Audit existing distributor plant per Honeywell product specifications.
Provide technical support in resolving Solstice yf product quality issues and customer complains.
Supervising GC and GC/MS lab in BRL - Coach and mentor chemists and technicians to continuously improve technical capabilities and business acumen.
Subject-matter expert in analytical chemistry - Identify key analytical sciences and instrumentations required for FP and PMT growth business.
Collaborate with other Honeywell research laboratories, located in Chicago and Shanghai to resolve analytical problem/issues and in sharing analytical resources.
Experience
2-5 Years
Level
Junior
Education
Ph.D. In Chemistry
Associate Principal Scientist Resume
Objective : A 20 years experienced Polymer Material Scientist with experience in products and processes development and test method validation.
Skills : Polymer Surface Modification, Nano And Micro Particles Synthesis And Production.
Description :
Developed novel hydrophilic virus filtration membranes based on Polyvinylidene fluoride and Polyethersulfone.
Developed new formulations for supported microfiltration membranes and scaled up at the membrane casting machines.
Applied mixture design to optimize the formulation and finished the project 10 months earlier than planned.
Solved the production issue for an unsupported microfiltration membrane using Six Sigma methodology.
Production efficiency increased 100% by cutting the waste.
Controlled the extractables from hydrophilic polypropylene membranes by inventing new surface modification process based on photochemical reaction.
Unique features of nitrocellulose membrane of Pall were compared with that of competitors by thoroughly investigating the physical, chemical, structural and mechanical properties.
Experience
2-5 Years
Level
Junior
Education
MBA
Lead Principal Scientist Resume
Summary : Working within an organization where can utilize strong work ethic and dedication to providing the best service possible. Enjoy working with a team to collaboratively realize preventative actions and continuous product and process improvements.
Provided analysis and data interpretation of air and surface samples for fungi and laboratory reports of findings.
Provided updated aerobiology knowledge and personal experience identifying fungal spores.
Developed a company-wide spore interpretation manual.
Increased reliability of investigations, technical reports, and remediation protocols of homes experiencing moisture problems and fungal growth.
Increased effectiveness of company operations by reducing staff time in generating remediation protocols of homes experiencing moisture problems and fungal infestation.
Assisted senior management in developing future service offerings in the area of indoor air quality.
Increased the visibility of company activities.
Experience
10+ Years
Level
Senior
Education
Ph.D. In Aerobiology
Principal Scientist/Executive Resume
Headline : Highly skilled molecular and cellular biologist with extensive hands-on experience in recombinant DNA techniques, mammalian cell culture and cell-based assay development.
Skills : Microsoft Office, GraphPad Prism.
Description :
Investigated the use of mouse embryonic stem cells derived from diversity-outbred mice as a tool for determining molecular basis of cytotoxicity.
Expanded and banked 600 clone of mouse embryonic stem cells (mESC).
Set up high throughput lab automation consisting of Biomek FX liquid handler integrated with cytomat hotel and cytomat incubator.
Selected compounds for screening by determining and optimizing compound concentrations.
Developed and implemented a protocol to screen 320 mES cell lines using 86 compounds at 14 concentrations.
Analyzes data using GraphPad Prism and wrote reports.
Developed and documented standard operating proceedures (SOPs) to be used by other scientist.
Experience
5-7 Years
Level
Executive
Education
Diagnostics
Principal Scientist/Analyst Resume
Headline : A highly-motivated senior-level scientist with the extensive experience in Cell Biology, Oncology and Immunology, demonstrated ability to work independently or in a team environment.
Skills : GxP, R&D and analytical.
Description :
Managed the In-Process Testing and Test Reagent manufacturing group.
Optimized testing and manufacturing schedule so as to reduce downtime and prevent backorders.
Designed new training system to cross train employees on all assays and increase efficiency.
Reviewed all in-process testing and release testing data and designed investigations into Out of Specification results.
Planned and supervised on-going stability studies for manufactured reagents.
Performed employee interviews, evaluations and reviews.
Designed Process Validation protocols as well cleaning validation experiments and studies.
Assisted in transfers of new products from development.
Experience
5-7 Years
Level
Executive
Education
Ph.D
Principal Scientist Resume
Headline : Highly qualified Principal Scientist with experience in the industry. Enjoy creative problem solving and getting exposure on multiple projects, and the collaborative environment on which company prides itself.
Participated in project meetings for the Rare Disease, Immunoscience, and Inflammation-Remodeling RUs as well as Discovery Bioanalytical group meetings.
Provided high quality and efficient bioanalytical support for several studies across all of the therapeutic areas, including bioanalysis, reporting and archiving.
Effectively communicated with PRs regarding possible bioanalytical issues.
Developed conjugated payload assay for HDAC antibody-drug conjugate.
Performed non-specific binding experiments for Ertugliflozin in human urine.
Participated with the development of a Hamilton STAR standard, QC, and extraction program.
Led scientific efforts to prepare preclinical candidates and generic MRCM and targeted nuclear medicine conjugates.
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